Sodium lauroyl glutamate

For research use only. Not for therapeutic Use.

  • CAT Number: I036477
  • CAS Number: 29923-31-7
  • Molecular Formula: C17H30NNaO5
  • Molecular Weight: 351.41
  • Purity: 98%
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Sodium lauroyl glutamate (Cat.No:I036477) is derived from glutamic acid (an amino acid), lauric acid (a fatty acid derived from renewable plant resources) and sodium. It is used as a gentle cleanser more suitable for sensitive skin.


Catalog Number I036477
CAS Number 29923-31-7
Synonyms

Sodium lauroyl glutamate; Hostapon CLG; Amisoft LS 11; Acylglutamate LS-11; Sodium N-lauroylglutamate;

Molecular Formula C17H30NNaO5
Purity 98%
Solubility Soluble in DMSO
Appearance Solid powder
Storage Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
IUPAC Name sodium (S)-4-carboxy-2-dodecanamidobutanoate
InChI InChI=1S/C17H31NO5.Na/c1-2-3-4-5-6-7-8-9-10-11-15(19)18-14(17(22)23)12-13-16(20)21;/h14H,2-13H2,1H3,(H,18,19)(H,20,21)(H,22,23);/q;+1/p-1/t14-;/m0./s1
InChIKey IWIUXJGIDSGWDN-UQKRIMTDSA-M
SMILES O=C(O)CC[C@@H](C([O-])=O)NC(CCCCCCCCCCC)=O.[Na+]
Reference

1: Burnett CL, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Andersen FA. Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics. Int J Toxicol. 2017 May/Jun;36(1_suppl):17S-56S. doi: 10.1177/1091581816686048. PubMed PMID: 28553738.
2: Ariki R, Hirano A, Arakawa T, Shiraki K. Drug solubilization effect of lauroyl-L-glutamate. J Biochem. 2012 Jan;151(1):27-33. doi: 10.1093/jb/mvr117. Epub 2011 Sep 23. PubMed PMID: 21949409.
3: Corazza M, Lauriola MM, Bianchi A, Zappaterra M, Virgili A. Irritant and sensitizing potential of eight surfactants commonly used in skin cleansers: an evaluation of 105 patients. Dermatitis. 2010 Sep-Oct;21(5):262-8. PubMed PMID: 20920412.
4: Chen Z, Liu J, Han Y. Rapid and sensitive determination of proteins by enhanced resonance light scattering spectroscopy of sodium lauroyl glutamate. Talanta. 2007 Feb 28;71(3):1246-51. doi: 10.1016/j.talanta.2006.06.025. Epub 2006 Jul 27. PubMed PMID: 19071440.
5: Rosa M, Rosa Infante M, Miguel Mda G, Lindman B. Spontaneous formation of vesicles and dispersed cubic and hexagonal particles in amino acid-based catanionic surfactant systems. Langmuir. 2006 Jun 20;22(13):5588-96. PubMed PMID: 16768481.
6: Kawasaki Y, Quan D, Sakamoto K, Maibach HI. Electron resonance studies on the influence of anionic surfactants on human skin. Dermatology. 1997;194(3):238-42. PubMed PMID: 9187840.
7: Lee CH, Kawasaki Y, Maibach HI. Effect of surfactant mixtures on irritant contact dermatitis potential in man: sodium lauroyl glutamate and sodium lauryl sulphate. Contact Dermatitis. 1994 Apr;30(4):205-9. PubMed PMID: 8033544.

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