For research use only. Not for therapeutic Use.
Sodium Salicylate inhibits cyclo-oxygenase-2 (COX-2) activity independently of transcription factor (NF-κB) activation.
| Catalog Number | I013883 |
| CAS Number | 54-21-7 |
| Molecular Formula | C₇H₅NaO₃ |
| Purity | ≥95% |
| Target | COX Autophagy |
| Solubility | H2O: ≥ 200 mg/mL |
| IUPAC Name | sodium;2-hydroxybenzoate |
| InChI | InChI=1S/C7H6O3.Na/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1 |
| InChIKey | ABBQHOQBGMUPJH-UHFFFAOYSA-M |
| SMILES | C1=CC=C(C(=C1)C(=O)[O-])O.[Na+] |
| Reference | [1]. Mitchell JA, et al. Sodium salicylate inhibits cyclo-oxygenase-2 activity independently of transcription factor (nuclear factor kappaB) activation: role of arachidonic acid. Mol Pharmacol. 1997 Jun;51(6):907-12.<br>[2]. Nixon M, et al. Salicylate downregulates 11β-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization. Diabetes. 2012 Apr;61(4):790-6. |
