For research use only. Not for therapeutic Use.
<p>It is an adrenergic and serotonergic stimulant and so it is a CNS stimulant.</p><p>It has antiarrhythmic activities.</p><br />C<SUB>20</SUB>-diterpenoid alkaloid<!–C<SUB>22</SUB>H<SUB>31</SUB>NO<SUB>3</SUB>–>, from plants of the <I>Aconitum</I> genus, Ranunculaceae</br><p>Its antiarrhythmic and CNS stimulant effects are 25 times as potent as <strong>Quinidine </strong>and 2 times less toxic. The stimulant effect on the CNS is due to adrenergic and serotonergic stimulation in the reticular formation:</p><p>- it causes desynchronization of cortex and sub-cortex action potential rhythms;</p><p>- it enhances and prolongs the /reaction of activation/ after visual and phonic stimulation;</p><p>- it suppresses the electroencephalogram modifications due to intravenous injection of 2 mg/kg <strong>Chlorpromazine</strong>.</p></br>
| Catalog Number | R035481 |
| CAS Number | 509-24-0 |
| Synonyms | Bullatine G; Napellonin; Napellonine; Songorin; Xuan-Wu 2; Zongorine; [3R-(3α,6β,6aα,6bα,9β,11α,11aβ,12α,12aβ,14R*)]-1-Ethyldodecahydro-6,11-dihydroxy-3-methyl-10-methylene-12,3,6a-ethanylylidene-9,11a-methanoazuleno[2,1-b]azocin-8(9H)-one; (3R,6S,6a |
| Molecular Formula | C₂₂H₃₁NO₃ |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Storage | Store at -20C |
| Reference | – De la Fuente et al., Heterocycles (1988). 27:1109<br /><br /><br /><br /> |
