For research use only. Not for therapeutic Use.
SOS1-IN-14（Cat No.:I042745）is a selective small molecule inhibitor targeting the SOS1 protein, a key regulator of RAS signaling. SOS1 is involved in the activation of RAS, which plays a crucial role in cell growth, differentiation, and survival. Dysregulated RAS signaling is often implicated in various cancers, including pancreatic, lung, and colorectal cancers. By inhibiting SOS1, SOS1-IN-14 disrupts this signaling pathway, potentially reducing tumor growth and enhancing the effectiveness of existing cancer therapies. Researchers are exploring its therapeutic potential in oncology, focusing on its ability to target RAS-driven tumors and improve patient outcomes.
| CAS Number | 2793405-20-4 |
| Synonyms | 1-[(7S)-17-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-15-methyl-10-oxa-2,5,14,16-tetrazatetracyclo[9.8.0.02,7.013,18]nonadeca-1(11),12,14,16,18-pentaene-5-carbonyl]cyclopropane-1-carbonitrile |
| Molecular Formula | C29H29F3N6O2 |
| Purity | ≥95% |
| IUPAC Name | 1-[(7S)-17-[[(1R)-1-[3-(difluoromethyl)-2-fluorophenyl]ethyl]amino]-15-methyl-10-oxa-2,5,14,16-tetrazatetracyclo[9.8.0.02,7.013,18]nonadeca-1(11),12,14,16,18-pentaene-5-carbonyl]cyclopropane-1-carbonitrile |
| InChI | InChI=1S/C29H29F3N6O2/c1-16(19-4-3-5-20(25(19)30)26(31)32)34-27-21-12-23-24(13-22(21)35-17(2)36-27)40-11-6-18-14-37(9-10-38(18)23)28(39)29(15-33)7-8-29/h3-5,12-13,16,18,26H,6-11,14H2,1-2H3,(H,34,35,36)/t16-,18+/m1/s1 |
| InChIKey | UVNQICXVXBBWBT-AEFFLSMTSA-N |
| SMILES | CC1=NC2=CC3=C(C=C2C(=N1)N[C@H](C)C4=C(C(=CC=C4)C(F)F)F)N5CCN(C[C@@H]5CCO3)C(=O)C6(CC6)C#N |
