For research use only. Not for therapeutic Use.
Soularubinone(CAT: I036518) is a potent inhibitor of NADH:ubiquinone oxidoreductase, also known as Complex I of the mitochondrial electron transport chain. By disrupting oxidative phosphorylation, it reduces ATP production, making it a valuable tool for studying mitochondrial function and energy metabolism. Soularubinone is particularly relevant in the metabolic diseases field, where mitochondrial dysfunction is implicated in conditions like diabetes and neurodegenerative disorders. Its application extends to research on oxidative stress and cellular respiration, providing critical insights into therapeutic strategies targeting mitochondrial pathways.
| CAS Number | 74156-49-3 |
| Synonyms | Soularubinone |
| Molecular Formula | C25H34O10 |
| Purity | 98% |
| Solubility | Soluble in DMSO |
| Appearance | Solid powder |
| Storage | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
| IUPAC Name | [(1S,4R,5R,6R,7S,8R,11R,13S,17S,18S,19R)-4,5,17-trihydroxy-6,14,18-trimethyl-9,16-dioxo-3,10-dioxapentacyclo[9.8.0.01,7.04,19.013,18]nonadec-14-en-8-yl] 3-hydroxy-3-methylbutanoate |
| InChI | InChI=1S/C25H34O10/c1-10-6-13(26)19(29)23(5)12(10)7-14-24-9-33-25(32,21(23)24)18(28)11(2)16(24)17(20(30)34-14)35-15(27)8-22(3,4)31/h6,11-12,14,16-19,21,28-29,31-32H,7-9H2,1-5H3/t11-,12+,14-,16-,17-,18-,19-,21-,23-,24+,25+/m1/s1 |
| InChIKey | BASHMUPTLJHSQJ-ZGXGNEARSA-N |
| SMILES | C[C@@H]1[C@@H]2[C@H](C(=O)O[C@H]3[C@@]24CO[C@@]([C@@H]1O)([C@@H]4[C@@]5([C@@H](C3)C(=CC(=O)[C@H]5O)C)C)O)OC(=O)CC(C)(C)O |
