SP-420

• CAT Number: I005435
• CAS Number: 911714-45-9
• Molecular Formula: C16H21NO6S
• Molecular Weight: 355.41
• Purity: ≥95%
• Synonyms: SP420
• Solubility: DMSO: ≥ 38 mg/mL
• Storage: Store at -20°C
• IUPAC Name: (4S)-2-[2-hydroxy-4-[2-(2-methoxyethoxy)ethoxy]phenyl]-4-methyl-5H-1,3-thiazole-4-carboxylic acid
• InChI: InChI=1S/C16H21NO6S/c1-16(15(19)20)10-24-14(17-16)12-4-3-11(9-13(12)18)23-8-7-22-6-5-21-2/h3-4,9,18H,5-8,10H2,1-2H3,(H,19,20)/t16-/m1/s1
• InChIKey: YASYAEVZKXPYIZ-MRXNPFEDSA-N
• SMILES: C[C@@]1(CSC(=N1)C2=C(C=C(C=C2)OCCOCCOC)O)C(=O)O

SP-420（Cat No.:I005435）is a selective and potent inhibitor of the enzyme phosphodiesterase 4 (PDE4), which plays a key role in regulating inflammation and immune responses. By inhibiting PDE4, SP-420 increases levels of cyclic AMP (cAMP) within cells, leading to the suppression of pro-inflammatory cytokines and the modulation of immune cell activity. SP-420 has been investigated for its potential in treating inflammatory diseases such as asthma, chronic obstructive pulmonary disease (COPD), and autoimmune conditions. While promising in preclinical and clinical studies, further research is needed to fully assess its efficacy, safety, and therapeutic applications.