SpdSyn binder-1

• CAT Number: I042474
• CAS Number: 251106-30-6
• Molecular Formula: C21H22N4O
• Molecular Weight: 346.43
• Purity: ≥95%
• Synonyms: 3H-benzimidazol-5-yl-[4-[(E)-3-phenylprop-2-enyl]piperazin-1-yl]methanone
• InChI: InChI=1S/C21H22N4O/c26-21(18-8-9-19-20(15-18)23-16-22-19)25-13-11-24(12-14-25)10-4-7-17-5-2-1-3-6-17/h1-9,15-16H,10-14H2,(H,22,23)/b7-4+
• InChIKey: OHZGXXXQMBAXGH-QPJJXVBHSA-N
• SMILES: C1CN(CCN1CC=CC2=CC=CC=C2)C(=O)C3=CC4=C(C=C3)N=CN4

SpdSyn binder-1 is a weak binder, which binds in the active site of plasmodium falciparum spermidine synthase. SpdSyn binder-1 can be used for the research of malaria[1].

Reference

[1]. Micael Jacobsson, et al. Identification of Plasmodium falciparum spermidine synthase active site binders through structure-based virtual screening. J Med Chem. 2008 May 8;51(9):2777-86.
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