For research use only. Not for therapeutic Use.
Spesolimab(Cat No.:I042200)is a monoclonal antibody that targets and inhibits the interleukin-36 receptor (IL-36R), which plays a key role in the inflammatory processes of several autoimmune diseases. Overactivation of IL-36R is associated with conditions like generalized pustular psoriasis and other skin-related disorders. By blocking this receptor, spesolimab aims to reduce inflammation, alleviate symptoms, and improve skin lesions in affected patients. It is being studied in clinical trials for its safety, efficacy, and potential to treat autoimmune diseases with excessive IL-36R activity, offering a new therapeutic approach.
Catalog Number | I042200 |
CAS Number | 2097104-58-8 |
Purity | ≥95% |