For research use only. Not for therapeutic Use.
Sphingosine (d17:1) is a 17-carbon sphingosine found in human skin. Sphingosine (d17:1) can be phosphorylated by sphingosine kinases to produce C-17 sphingosine-1-phosphate. Sphingosine C-17 was used as an internal standard for spectral analysis of sphingoid compounds[1][2][3].
| Catalog Number | R061857 |
| CAS Number | 6918-48-5 |
| Synonyms | (E,2S,3R)-2-aminoheptadec-4-ene-1,3-diol |
| Molecular Formula | C17H35NO2 |
| Purity | ≥95% |
| InChI | InChI=1S/C17H35NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(20)16(18)15-19/h13-14,16-17,19-20H,2-12,15,18H2,1H3/b14-13+/t16-,17+/m0/s1 |
| InChIKey | RBEJCQPPFCKTRZ-LHMZYYNSSA-N |
| SMILES | CCCCCCCCCCCCC=CC(C(CO)N)O |
| Reference | [1]. Stewart ME, et al. Free sphingosines of human skin include 6-hydroxysphingosine and unusually long-chain dihydrosphingosines. J Invest Dermatol. 1995 Oct;105(4):613-8. [2]. Hong JH, et al. K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling. J Invest Dermatol. 2008 Sep;128(9):2166-78. [3]. Choi CH, et al. Sphingosine 1-phosphate and sphingosine kinase activity during chicken embryonic development. Arch Pharm Res. 2007 Apr;30(4):502-6. |
