Spilanthol A mixture of (2E, 6Z, 8E) >80%; (2E, 6E, 8E); and (2E, 6Z, 8Z)

• CAT Number: R059013
• CAS Number: 25394-57-4
• Molecular Formula: C₁₄H₂₃NO
• Molecular Weight: 221.34
• Purity: ≥95%
• Synonyms: (2E,6Z,8E)-N-(2-Methylpropyl)-2,6,8-decatrienamide; (E,E,Z)-N-(2-Methylpropyl)-?2,6,8-decatrienamide; (E,E,Z)- N-Isobutyl-2,6,8-decatrienamide; Affinin; 2E,6Z,8E-Decatrienoic Acid N-Isobutylamide; N-Isobutyldeca-trans-2,cis-?6,trans-8-trienamide
• Target: Bacterial
• IUPAC Name: (2E,6Z,8E)-N-(2-methylpropyl)deca-2,6,8-trienamide
• InChI: InChI=1S/C14H23NO/c1-4-5-6-7-8-9-10-11-14(16)15-12-13(2)3/h4-7,10-11,13H,8-9,12H2,1-3H3,(H,15,16)/b5-4+,7-6-,11-10+
• InChIKey: BXOCHUWSGYYSFW-HVWOQQCMSA-N
• SMILES: CC=CC=CCCC=CC(=O)NCC(C)C

Spilanthol（Cat No.:R059013） is a natural compound, primarily composed of three isomers: (2E, 6Z, 8E), (2E, 6E, 8E), and (2E, 6Z, 8Z), with the predominant isomer being (2E, 6Z, 8E) constituting over 80% of the mixture. It is commonly found in plants like the Acmella oleracea, also known as the “toothache plant,” and is renowned for its analgesic and antimicrobial properties. Spilanthol is utilized in traditional medicine for pain relief, and recent studies have explored its potential in cosmetics and dermatology due to its ability to induce skin firmness and reduce wrinkles, making it a promising candidate in the skincare industry.

Reference

1.Khadir, H., et al.: Pestic. Sci., 25, 329 (1989)
2.Cech, Nadja B., et al. "Liver enzyme-mediated oxidation of Echinacea purpurea alkylamides: production of novel metabolites and changes in immunomodulatory activity." Planta medica 72.15 (2006): 1372.
3.Saritha, K. V., and C. V. Naidu. "Direct shoot regeneration from leaf explants of Spilanthes acmella." Biologia plantarum 52.2 (2008): 334-338.