Spinosyn A aglycone

• CAT Number: R008636
• CAS Number: 149560-97-4
• Molecular Formula: C24H34O5
• Molecular Weight: 402.5
• Purity: ≥95%
• Storage: -20°C
• IUPAC Name: (1S,2R,5S,7R,9R,10S,14R,15S,19S)-19-ethyl-7,15-dihydroxy-14-methyl-20-oxatetracyclo[10.10.0.02,10.05,9]docosa-3,11-diene-13,21-dione
• InChI: InChI=1S/C24H34O5/c1-3-16-5-4-6-22(26)13(2)24(28)21-11-19-17(20(21)12-23(27)29-16)8-7-14-9-15(25)10-18(14)19/h7-8,11,13-20,22,25-26H,3-6,9-10,12H2,1-2H3/t13-,14-,15-,16+,17-,18-,19-,20+,22+/m1/s1
• InChIKey: DIHUILSVOGYVDG-MRAVEKNJSA-N
• SMILES: CCC1CCCC(C(C(=O)C2=CC3C4CC(CC4C=CC3C2CC(=O)O1)O)C)O

Spinosyn A aglycone(CAS 149560-97-4) is an acid degradation product produced by hydrolysis of both saccharide groups on spinosyn A, the major component of the commercial insecticide, spinosad. Spinosyn A aglycone is only weakly active as an insecticide as the saccharides are considered essential for potent activity. Despite the importance of spinosyns as agro-chemical insecticides and more recently as animal health products, there are few published reports of the biological activity or the levels of spinosyn A aglycone in animals or in the environment.

Reference

1.Creemer, Lawrence C., Herbert A. Kirst, and Jonathan W. Paschal. "Conversion of spinosyn A and spinosyn D to their respective 9-and 17-pseudoaglycones and their aglycones." The Journal of antibiotics 51.8 (1998): 795-800.
2,Cleveland, Cheryl B., et al. "Environmental fate of spinosad. 1. Dissipation and degradation in aqueous systems." Journal of agricultural and food chemistry 50.11 (2002): 3244-3256.