For research use only. Not for therapeutic Use.
Spiperone hydrochloride (Cat.No:I010351) is a 5-HT<sub>2A</sub> serotonin and selective D<sub>2</sub>-like dopamine receptor antagonist (K<sub>i</sub> values are 0.06, 0.6, 0.08, ~ 350, ~ 3500 nM for D<sub>2</sub>, D<sub>3</sub>, D<sub>4</sub>, D<sub>1</sub> and D<sub>5</sub> receptors respectively). Antipsychotic.
| Catalog Number | I010351 |
| CAS Number | 2022-29-9 |
| Synonyms | 8-[4-(4-Fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one hydrochloride |
| Molecular Formula | C23H27ClFN3O2 |
| Purity | ≥95% |
| Target | Neuronal Signaling |
| Solubility | Soluble to 100 mM in DMSO |
| Storage | Store at RT |
| IUPAC Name | 8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;hydrochloride |
| InChI | InChI=1S/C23H26FN3O2.ClH/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20;/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29);1H |
| InChIKey | QUIKMLCZZMOBLH-UHFFFAOYSA-N |
| SMILES | C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CCCC(=O)C4=CC=C(C=C4)F.Cl |
