Spiperone

• CAT Number: R008051
• CAS Number: 749-02-0
• Molecular Formula: C23H26FN3O2
• Molecular Weight: 395.478
• Purity: ≥95%
• Synonyms: 8-[4-(4-Fluprophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one;?4-Phenyl-8-[3-(4-fluorobenzoyl)propyl]-1-oxo-2,4,8-triazaspiro[4,5]decane; Spiropitan; Spiroperidol; Spiroperidone
• Target: Neuronal Signaling
• Storage: -20°C
• IUPAC Name: 8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one
• InChI: InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)
• InChIKey: DKGZKTPJOSAWFA-UHFFFAOYSA-N
• SMILES: C1CN(CCC12C(=O)NCN2C3=CC=CC=C3)CCCC(=O)C4=CC=C(C=C4)F

Spiperone is a potent butyrophenone derivative used extensively in pharmacological research. It functions as a selective antagonist for dopamine D2 receptors, making it crucial in studying neurological and psychiatric disorders. Additionally, Spiperone has applications in receptor-binding assays and PET imaging, aiding in the visualization of brain activity. Its high specificity and affinity for serotonin and dopamine receptors also make it valuable for exploring psychotropic drug mechanisms. This compound’s reliability ensures precise experimental outcomes in neuropharmacological research and drug development.