Spiramycin

• CAT Number: R004364
• CAS Number: 8025-81-8
• Molecular Formula: C43H74N2O14 (Spiramycin I, R = H)
• Molecular Weight: 843.10
• Purity: ≥95%
• Synonyms: Formacidine;NSC 55926;Rovamycine
• Target: Bacterial
• Storage: 2-8°C
• IUPAC Name: 2-[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4,5-dihydroxy-4,6-dimethyloxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-10-[(2R,5S,6R)-5-(dimethylamino)-6-methyloxan-2-yl]oxy-4-hydroxy-5-methoxy-9,16-dimethyl-2-oxo-1-oxacyclohexadeca-11,13-dien-7-yl]acetaldehyde
• InChI: InChI=1S/C43H74N2O14/c1-24-21-29(19-20-46)39(59-42-37(49)36(45(9)10)38(27(4)56-42)58-35-23-43(6,51)41(50)28(5)55-35)40(52-11)31(47)22-33(48)53-25(2)15-13-12-14-16-32(24)57-34-18-17-30(44(7)8)26(3)54-34/h12-14,16,20,24-32,34-42,47,49-51H,15,17-19,21-23H2,1-11H3/b13-12+,16-14+/t24-,25-,26-,27-,28+,29+,30+,31-,32+,34+,35+,36-,37-,38-,39+,40+,41+,42+,43-/m1/s1
• InChIKey: ACTOXUHEUCPTEW-CEUOBAOPSA-N
• SMILES: C[C@@H]1C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]([C@@H](CC(=O)O1)O)OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)O)(C)O)N(C)C)O)CC=O)C)O[C@H]4CC[C@@H]([C@H](O4)C)N(C)C

Cefacetrile（Cat No.:R004364）is a broad-spectrum cephalosporin antibiotic used for the treatment of various bacterial infections. It is effective against both Gram-positive and Gram-negative organisms, including staphylococci, streptococci, and certain enterobacteria. Cefacetrile works by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. It is commonly prescribed for respiratory, urinary tract, and skin infections. Administered via intravenous or intramuscular injection, cefacetrile demonstrates high stability in the presence of β-lactamases, making it a reliable option in resistant bacterial strains. It is generally well-tolerated with minimal side effects.

Reference

Lovmar, Martin, and Tanel Tenson. /The Mechanism of Action of Macrolides, Lincosamides and Streptogramin B Reveals the Nascent Peptide Exit Path in the Ribosome./Journal of Molecular Microbiology 330.5 (2003): 1005-014.