Spironolactone-d7

• CAT Number: S000850
• Molecular Formula: C24H25D7O4S
• Molecular Weight: 423.62
• Purity: ≥95%
• IUPAC Name: S-[(7R,8R,9S,10R,13S,14S,17R)-2,2,4,4',4',6,7-heptadeuterio-10,13-dimethyl-3,5'-dioxospiro[6,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate
• InChI: InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1/i4D2,7D2,12D,13D,19D/t13?,17-,18-,19+,21+,22-,23-,24+
• InChIKey: LXMSZDCAJNLERA-BLXBWACRSA-N
• SMILES: CC(=O)SC1CC2=CC(=O)CCC2(C3C1C4CCC5(C4(CC3)C)CCC(=O)O5)C

Spironolactone-d7（Cat No.:S000850） is a deuterated form of spironolactone where seven hydrogen atoms are replaced with deuterium, enhancing its molecular stability with the formula C24H25D7O4S. This stable isotope-labeled diuretic and antihypertensive agent is used in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy to improve the detection and quantification of metabolites in pharmacokinetic and metabolic studies. Spironolactone-d7 is crucial for researching the drug’s therapeutic effects and metabolism, particularly in treatments related to heart failure, hypertension, and conditions related to excess aldosterone, offering deeper insights into its pharmacological dynamics.