Spironolactone-d7(Cat No.:S000850) is a deuterated form of spironolactone where seven hydrogen atoms are replaced with deuterium, enhancing its molecular stability with the formula C24H25D7O4S. This stable isotope-labeled diuretic and antihypertensive agent is used in mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy to improve the detection and quantification of metabolites in pharmacokinetic and metabolic studies. Spironolactone-d7 is crucial for researching the drug’s therapeutic effects and metabolism, particularly in treatments related to heart failure, hypertension, and conditions related to excess aldosterone, offering deeper insights into its pharmacological dynamics.
Catalog Number | S000850 |
Molecular Formula | C24H25D7O4S |
Purity | ≥95% |
IUPAC Name | S-[(7R,8R,9S,10R,13S,14S,17R)-2,2,4,4',4',6,7-heptadeuterio-10,13-dimethyl-3,5'-dioxospiro[6,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate |
InChI | InChI=1S/C24H32O4S/c1-14(25)29-19-13-15-12-16(26)4-8-22(15,2)17-5-9-23(3)18(21(17)19)6-10-24(23)11-7-20(27)28-24/h12,17-19,21H,4-11,13H2,1-3H3/t17-,18-,19+,21+,22-,23-,24+/m0/s1/i4D2,7D2,12D,13D,19D/t13?,17-,18-,19+,21+,22-,23-,24+ |
InChIKey | LXMSZDCAJNLERA-BLXBWACRSA-N |
SMILES | CC(=O)SC1CC2=CC(=O)CCC2(C3C1C4CCC5(C4(CC3)C)CCC(=O)O5)C |