For research use only. Not for therapeutic Use.
SPOP-i-6lc is a selective speckle-type POZ protein (SPOP) E3 ubiquitin ligase inhibitor with IC50 of 2.1 μM and 3.5 μM, in A498 and OS-RC-2 cell lines, respectively. In vitro, It suppresses viability and proliferation of A498 and OS-RC-2 kidney cancer cell lines.
Catalog Number | I047471 |
CAS Number | 2136270-56-7 |
Molecular Formula | C26H31N7O2S |
Purity | ≥95% |
Reference | [1] Dong Z, et al. J Med Chem. 2020 May 14;63(9):4849-4866. |