For research use only. Not for therapeutic Use.
SPP (Cat No.: I018036) is a versatile degradable linker that incorporates disulfide bonds, making it a valuable component in the synthesis of cytotoxic compound-linker conjugates. This linker plays a crucial role in the development of drug delivery systems, allowing for the controlled release of cytotoxic compounds in targeted applications. Researchers rely on SPP to create innovative conjugates with the potential for improved therapeutic outcomes. For additional information or specific inquiries concerning SPP, please do not hesitate to contact us.
| Catalog Number | I018036 |
| CAS Number | 341498-08-6 |
| Molecular Formula | C₁₄H₁₆N₂O₄S₂ |
| Purity | ≥95% |
| Target | ADC Linker |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 4-(pyridin-2-yldisulfanyl)pentanoate |
| InChI | InChI=1S/C14H16N2O4S2/c1-10(21-22-11-4-2-3-9-15-11)5-8-14(19)20-16-12(17)6-7-13(16)18/h2-4,9-10H,5-8H2,1H3 |
| InChIKey | GTBCXYYVWHFQRS-UHFFFAOYSA-N |
| SMILES | CC(CCC(=O)ON1C(=O)CCC1=O)SSC2=CC=CC=N2 |
| Reference | [1]. Widdison W, et al. Metabolites of antibody-maytansinoid conjugates: characteristics and in vitro potencies. Mol Pharm. 2015 Jun 1;12(6):1762-73. |
