SPT-IN-1

• CAT Number: I036558
• CAS Number: 1933533-18-6
• Molecular Formula: C22H24N2O3
• Molecular Weight: 364.44
• Purity: ≥95%
• Synonyms: 2-[4-(6-heptanoylimidazo[1,2-a]pyridin-8-yl)phenyl]acetic acid
• InChI: InChI=1S/C22H24N2O3/c1-2-3-4-5-6-20(25)18-14-19(22-23-11-12-24(22)15-18)17-9-7-16(8-10-17)13-21(26)27/h7-12,14-15H,2-6,13H2,1H3,(H,26
• InChIKey: MMYRYMMKMUTPBB-UHFFFAOYSA-N
• SMILES: CCCCCCC(=O)C1=CN2C=CN=C2C(=C1)C3=CC=C(C=C3)CC(=O)O

SPT-IN-1（Cat No.:I036558）is a selective small molecule inhibitor of serine palmitoyltransferase (SPT), an enzyme responsible for the first step in sphingolipid biosynthesis. By inhibiting SPT, this compound disrupts the production of sphingolipids, which are crucial for membrane structure, signaling, and cell survival. SPT-IN-1 has shown potential in treating diseases associated with dysregulated sphingolipid metabolism, such as cancer, neurodegenerative disorders, and metabolic diseases. Its ability to modulate sphingolipid levels makes it a valuable tool for studying sphingolipid-related pathways and exploring therapeutic strategies for various diseases.