For research use only. Not for therapeutic Use.
SQ 29548, a high affinity radioligand, is a selective thromboxane-prostanoid (TP) receptor antagonist[1][2].
| Catalog Number | I011764 |
| CAS Number | 98672-91-4 |
| Synonyms | (Z)-7-[(1S,2R,3R,4R)-3-[[2-(phenylcarbamoyl)hydrazinyl]methyl]-7-oxabicyclo[2.2.1]heptan-2-yl]hept-5-enoic acid |
| Molecular Formula | C21H29N3O4 |
| Purity | ≥95% |
| InChI | InChI=1S/C21H29N3O4/c25-20(26)11-7-2-1-6-10-16-17(19-13-12-18(16)28-19)14-22-24-21(27)23-15-8-4-3-5-9-15/h1,3-6,8-9,16-19,22H,2,7,10-14H2,(H,25,26)(H2,23,24,27)/b6-1-/t16-,17+,18+,19-/m1/s1 |
| InChIKey | RJNDVCNWVBWHLY-YVUOLYODSA-N |
| SMILES | C1CC2C(C(C1O2)CC=CCCCC(=O)O)CNNC(=O)NC3=CC=CC=C3 |
| Reference | [1]. Isabella Lawandy, et al. Increased coronary arteriolar contraction to serotonin in juvenile pigs with metabolic syndrome. Mol Cell Biochem. 2019 Nov;461(1-2):57-64. [2]. A Hedberg, et al. Characterization of [5, 6-3H] SQ 29,548 as a high affinity radioligand, binding to thromboxane A2/prostaglandin H2-receptors in human platelets. J Pharmacol Exp Ther. 1988 Jun;245(3):786-92. |
