SR 16832

• CAT Number: I014686
• CAS Number: 2088135-12-8
• Molecular Formula: C17H12ClN3O4
• Molecular Weight: 357.75
• Purity: ≥95%
• Synonyms: 2-chloro-N-(6-methoxyquinolin-4-yl)-5-nitrobenzamide
• InChI: InChI=1S/C17H12ClN3O4/c1-25-11-3-5-15-13(9-11)16(6-7-19-15)20-17(22)12-8-10(21(23)24)2-4-14(12)18/h2-9H,1H3,(H,19,20,22)
• InChIKey: CVTZAGCRUDYUGB-UHFFFAOYSA-N
• SMILES: COC1=CC2=C(C=CN=C2C=C1)NC(=O)C3=C(C=CC(=C3)[N+](=O)[O-])Cl

SR 16832 is a dual site covalent PPARγ inhibitor that acts at orthosteric and allosteric sites[1].

Reference

[1]. Brust R, et al. Modification of the Orthosteric PPARγ Covalent Antagonist Scaffold Yields an Improved Dual-Site Allosteric Inhibitor. ACS Chem Biol. 2017 Apr 21;12(4):969-978.
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