SR-318

• CAT Number: I016855
• CAS Number: 2413286-32-3
• Molecular Formula: C₂₇H₃₃N₅O₂
• Molecular Weight: 459.58
• Purity: ≥95%
• Target: Apoptosis
• IUPAC Name: 5-amino-N-[[4-(3-cyclohexylpropylcarbamoyl)phenyl]methyl]-1-phenylpyrazole-4-carboxamide
• InChI: InChI=1S/C27H33N5O2/c28-25-24(19-31-32(25)23-11-5-2-6-12-23)27(34)30-18-21-13-15-22(16-14-21)26(33)29-17-7-10-20-8-3-1-4-9-20/h2,5-6,11-16,19-20H,1,3-4,7-10,17-18,28H2,(H,29,33)(H,30,34)
• InChIKey: HXNUFFCHRIWTRZ-UHFFFAOYSA-N
• SMILES: C1CCC(CC1)CCCNC(=O)C2=CC=C(C=C2)CNC(=O)C3=C(N(N=C3)C4=CC=CC=C4)N

SR-318（Cat No.:I016855）is a selective small molecule inhibitor known for its activity against specific targets involved in cellular signaling pathways, potentially including kinases or transcription factors. It has been explored in preclinical research for its role in modulating pathways linked to cancer progression or other diseases. By targeting key regulators in signaling cascades, SR-318 helps in understanding mechanisms behind cell proliferation, differentiation, or survival. It holds promise in investigating new therapeutic strategies for conditions characterized by dysregulated signaling pathways, such as certain cancers or immune-related disorders.

Reference

[1]. Röhm S, et al. Fast Iterative Synthetic Approach toward Identification of Novel Highly Selective p38 MAP Kinase Inhibitors. J Med Chem. 2019 Dec 12;62(23):10757-10782.