SR1555

For research use only. Not for therapeutic Use.

  • CAT Number: I036589
  • CAS Number: 1386439-51-5
  • Molecular Formula: C22H22F6N2O2
  • Molecular Weight: 460.41
  • Purity: ≥95%
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SR1555(Cat No.:I036589)is a selective small molecule inhibitor that targets the protein RORγt (Retinoic acid receptor-related orphan receptor gamma t), a key transcription factor involved in the differentiation and function of Th17 cells. Th17 cells play a crucial role in autoimmune diseases and inflammatory disorders. By inhibiting RORγt, SR1555 aims to modulate immune responses and reduce inflammation, making it a potential therapeutic candidate for conditions such as rheumatoid arthritis, multiple sclerosis, and inflammatory bowel disease. Its specificity for RORγt offers a targeted approach to managing autoimmune and inflammatory diseases.


CAS Number 1386439-51-5
Synonyms

1-[4-[[4-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]phenyl]methyl]piperazin-1-yl]ethanone

Molecular Formula C22H22F6N2O2
Purity ≥95%
IUPAC Name 1-[4-[[4-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]phenyl]methyl]piperazin-1-yl]ethanone
InChI InChI=1S/C22H22F6N2O2/c1-15(31)30-12-10-29(11-13-30)14-16-2-4-17(5-3-16)18-6-8-19(9-7-18)20(32,21(23,24)25)22(26,27)28/h2-9,32H,10-14H2,1H3
InChIKey LTFVNEZXOPUABB-UHFFFAOYSA-N
SMILES CC(=O)N1CCN(CC1)CC2=CC=C(C=C2)C3=CC=C(C=C3)C(C(F)(F)F)(C(F)(F)F)O
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