SRI-011381 hydrochloride

• CAT Number: I005876
• CAS Number: 2070014-88-7
• Molecular Formula: C20H32ClN3O
• Molecular Weight: 365.94
• Purity: ≥95%
• Target: TGF-beta
• Solubility: 10 mM in DMSO
• Storage: Store at +4C
• IUPAC Name: 1-benzyl-3-cyclohexyl-1-(piperidin-4-ylmethyl)urea;hydrochloride
• InChI: InChI=1S/C20H31N3O.ClH/c24-20(22-19-9-5-2-6-10-19)23(15-17-7-3-1-4-8-17)16-18-11-13-21-14-12-18;/h1,3-4,7-8,18-19,21H,2,5-6,9-16H2,(H,22,24);1H
• InChIKey: GPNMJVSGNMDOJN-UHFFFAOYSA-N
• SMILES: C1CCC(CC1)NC(=O)N(CC2CCNCC2)CC3=CC=CC=C3.Cl

SRI-011381 Hydrochloride(CAT: I005876) is a potent agonist of the TGF-β (Transforming Growth Factor-beta) signaling pathway, a critical regulator of cellular processes such as proliferation, differentiation, and immune modulation. By activating TGF-β signaling, it facilitates studies on fibrosis, cancer progression, and immune response modulation. SRI-011381 Hydrochloride is particularly valuable in oncology and immunology research, where TGF-β signaling plays dual roles in tumor suppression and progression. Its targeted mechanism offers insights into therapeutic strategies for TGF-β-related diseases, including fibrotic disorders and advanced cancers.