For research use only. Not for therapeutic Use.
SRI-43265 (compound 40) is an inhibitor of human antigen R protein (HuR) dimerization, and HuR multimers have been implicated in cancer and inflammatory pathogenesis[1].
| Catalog Number | I040010 |
| CAS Number | 2727872-88-8 |
| Synonyms | 3-(1H-indazol-5-yl)-N-methyl-N-(oxan-4-yl)imidazo[1,2-b]pyridazin-6-amine |
| Molecular Formula | C19H20N6O |
| Purity | ≥95% |
| InChI | InChI=1S/C19H20N6O/c1-24(15-6-8-26-9-7-15)19-5-4-18-20-12-17(25(18)23-19)13-2-3-16-14(10-13)11-21-22-16/h2-5,10-12,15H,6-9H2,1H3,(H,21,22) |
| InChIKey | UYAQXKNZGMAYGA-UHFFFAOYSA-N |
| SMILES | CN(C1CCOCC1)C2=NN3C(=NC=C3C4=CC5=C(C=C4)NN=C5)C=C2 |
| Reference | [1]. Preparation of imidazopyridazinamines as RNA-binding protein multimerization inhibitors and methods of use thereof. World Intellectual Property Organization, WO2021216757 A1 2021-10-28. |
