For research use only. Not for therapeutic Use.
(S,R,S)-AHPC-C4-NH2 dihydrochloride (CAT: I015412) is a dihydrochloride salt of (S,R,S)-AHPC-C4-NH2, which is a ligand used for the recruitment of the von Hippel-Lindau (VHL) protein. The compound is based on the VH032 scaffold and is designed to selectively bind to VHL. The interaction between (S,R,S)-AHPC-C4-NH2 and VHL can modulate the activity of VHL-associated proteins and pathways. This compound holds potential for the development of targeted therapies and further investigation in the field of cancer research and treatment.
| Catalog Number | I015412 |
| CAS Number | 2341796-78-7 |
| Molecular Formula | C₂₇H₄₁Cl₂N₅O₄S |
| Purity | ≥95% |
| Target | E3 Ligase Ligand-Linker Conjugates |
| Reference | [1]. Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9. |
