SRT 1720 Hydrochloride

• CAT Number: I000075
• CAS Number: 1001645-58-4
• Molecular Formula: C25H23N7OS • XHCl
• Molecular Weight: 506.00
• Purity: ≥95%
• Synonyms: N-[2-[3-(piperazin-1-ylmethyl)imidazo[2,1-b][1,3]thiazol-6-yl]phenyl]quinoxaline-2-carboxamide;hydrochloride
• Target: Sirtuin
• Solubility: DMSO: 38 mg/mL, H2O: <1 mg/mL
• Storage: 3 years -20C powder
• IC50: 0.16 μM(EC1.5 for SIRT1)
• InChI: 1S/C25H23N7OS.ClH/c33-24(22-13-27-20-7-3-4-8-21(20)28-22)29-19-6-2-1-5-18(19)23-15-32-17(16-34-25(32)30-23)14-31-11-9-26-10-12-31;/h1-8,13,15-16,26H,9-12,14H2,(H,29,33);1H
• InChIKey: DTGRRMPPXCRRIM-UHFFFAOYSA-N
• SMILES: C1CN(CCN1)CC2=CSC3=NC(=CN23)C4=CC=CC=C4NC(=O)C5=NC6=CC=CC=C6N=C5.Cl

SRT1720 Hydrochloride (Cat No.: I000075) is a selective activator of SIRT1, a NAD⁺-dependent deacetylase involved in cellular metabolism, aging, and stress resistance. By enhancing SIRT1 activity, SRT1720 promotes mitochondrial function, improves insulin sensitivity, and exhibits anti-inflammatory and neuroprotective effects. It has been extensively studied in metabolic and age-related diseases, including diabetes, cardiovascular disorders, and neurodegeneration. SRT1720’s role in longevity research highlights its potential as a therapeutic agent for age-related conditions, though further studies are needed to assess its clinical applicability.

Reference

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