For research use only. Not for therapeutic Use.
SRT3190 is an antagonist of CXCR2, used in the research of chemokine mediated diseases.
SRT3190 (Reference Example 2) is an antagonist of CXCR2, used in the research of chemokine mediated diseases[1].
| Catalog Number | I000756 |
| CAS Number | 1204707-73-2 |
| Synonyms | N-[2-[(2,3-difluorophenyl)methylsulfanyl]-6-[[(2S,3R)-3,4-dihydroxybutan-2-yl]amino]pyrimidin-4-yl]azetidine-1-sulfonamide |
| Molecular Formula | C18H23F2N5O4S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H23F2N5O4S2/c1-11(14(27)9-26)21-15-8-16(24-31(28,29)25-6-3-7-25)23-18(22-15)30-10-12-4-2-5-13(19)17(12)20/h2,4-5,8,11,14,26-27H,3,6-7,9-10H2,1H3,(H2,21,22,23,24)/t11-,14-/m0/s1 |
| InChIKey | QVKPEMXUBULFBM-FZMZJTMJSA-N |
| SMILES | CC(C(CO)O)NC1=CC(=NC(=N1)SCC2=C(C(=CC=C2)F)F)NS(=O)(=O)N3CCC3 |
| Reference | [1]. Premji Meghani, et al. Pyrimidyl sulfonaminde derivative and its use for the treatment of chemokine mediated diseases. WO2010007427A1 |
