For research use only. Not for therapeutic Use.
(S,S)-GSK321 is a (S,S)-enantiomer of GSK321[1].
| Catalog Number | I042666 |
| CAS Number | 1816272-20-4 |
| Synonyms | (7S)-1-[(4-fluorophenyl)methyl]-N-[3-[(1S)-1-hydroxyethyl]phenyl]-7-methyl-5-(1H-pyrrole-2-carbonyl)-6,7-dihydro-4H-pyrazolo[4,3-c]pyridine-3-carboxamide |
| Molecular Formula | C28H28FN5O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C28H28FN5O3/c1-17-14-33(28(37)24-7-4-12-30-24)16-23-25(27(36)31-22-6-3-5-20(13-22)18(2)35)32-34(26(17)23)15-19-8-10-21(29)11-9-19/h3-13,17-18,30,35H,14-16H2,1-2H3,(H,31,36)/t17-,18-/m0/s1 |
| InChIKey | IVFDDVKCCBDPQZ-ROUUACIJSA-N |
| SMILES | CC1CN(CC2=C1N(N=C2C(=O)NC3=CC=CC(=C3)C(C)O)CC4=CC=C(C=C4)F)C(=O)C5=CC=CN5 |
| Reference | [1]. Okoye-Okafor UC, et al. New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat Chem Biol. 2015 Nov;11(11):878-86. |
