(S,S,S)-AHPC hydrochloride

• CAT Number: I016406
• CAS Number: 2115897-23-7
• Molecular Formula: C₂₂H₃₁ClN₄O₃S
• Molecular Weight: 467.02
• Purity: ≥95%
• Target: Ligands for E3 Ligase

(S,S,S)-AHPC hydrochloride(CAT: I016406) is a hydrochloride salt form of (S,S,S)-AHPC, which is a small molecule ligand used in chemical biology and drug discovery research. (S,S,S)-AHPC is designed to selectively bind to and recruit von Hippel-Lindau (VHL) protein, leading to the degradation of specific target proteins through the ubiquitin-proteasome system. This compound has shown promise as a tool compound for studying protein degradation pathways and has potential applications in the development of targeted protein degradation-based therapies for various diseases.

Reference

[1]. Crew AP, et al. Identification and Characterization of Von Hippel-Lindau-Recruiting Proteolysis Targeting Chimeras (PROTACs) of TANK-Binding Kinase 1. J Med Chem. 2018 Jan 25;61(2):583-598.