S,S,S,S,S-Trandolapril Hydrochloride

• CAT Number: R025183
• CAS Number: 80828-32-6
• Molecular Formula: C24H35ClN2O5
• Molecular Weight: 467.003
• Purity: ≥95%
• Synonyms: (2S,3aS,7aS)-1-((S)-2-(((S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino)propanoyl)octahydro-1H-indole-2-carboxylic Acid Hydrochloride; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]octahydro-1H-Indole-2-carboxylic Aci
• Target: Angiotensin-converting Enzyme (ACE)
• Storage: -20°C
• IUPAC Name: (2S,3aS,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid;hydrochloride
• InChI: InChI=1S/C24H34N2O5.ClH/c1-3-31-24(30)19(14-13-17-9-5-4-6-10-17)25-16(2)22(27)26-20-12-8-7-11-18(20)15-21(26)23(28)29;/h4-6,9-10,16,18-21,25H,3,7-8,11-15H2,1-2H3,(H,28,29);1H/t16-,18-,19-,20-,21-;/m0./s1
• InChIKey: QNSWMJYOGMUVGO-PABIKWFMSA-N
• SMILES: CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2C3CCCCC3CC2C(=O)O.Cl

Indolapril hydrochloride is a novel nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor. The antihypertensive response to Indolapril hydrochloride (0.03-1.0 mg/kg p.o.) was found to correlate with inhibition of vascular tissue ACE.

Reference

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