For research use only. Not for therapeutic Use.
ST 034307(CAT: I011398) is an inhibitor of adenylyl cyclase 1 (AC1). It exhibits an IC50 value of 2.3 μM for AC1 inhibition. While it shows some selectivity for AC1 over other adenylyl cyclase isoforms, it does not display significant activity against AC8. ST 034307 has been shown to inhibit Ca2+/calmodulin-stimulated cAMP accumulation in hippocampal homogenates. Its ability to modulate adenylyl cyclase activity may have implications in various signaling pathways mediated by cAMP, such as those involved in neurotransmission and cellular responses to hormones and neurotransmitters.
| Catalog Number | I011398 |
| CAS Number | 133406-29-8 |
| Synonyms | 6-Chloro-2-(trichloromethyl)-4H-1-benzopyran-4-one |
| Molecular Formula | C10H4Cl4O2 |
| Purity | ≥95% |
| Target | Adenylate Cyclase |
| Solubility | Soluble to 100 mM in DMSO and to 20 mM in ethanol |
| Storage | Store at -20C |
| InChIKey | NTDHYMSVCBGQJF-UHFFFAOYSA-N |
