STAT3-IN-11

• CAT Number: I043495
• CAS Number: 2503096-50-0
• Molecular Formula: C20H17NO4
• Molecular Weight: 335.35
• Purity: ≥95%
• Synonyms: N-[2-(8-hydroxy-3-methyl-1,4-dioxonaphthalen-2-yl)ethyl]benzamide
• InChI: InChI=1S/C20H17NO4/c1-12-14(10-11-21-20(25)13-6-3-2-4-7-13)19(24)17-15(18(12)23)8-5-9-16(17)22/h2-9,22H,10-11H2,1H3,(H,21,25)
• InChIKey: XLSYRTJOLUDGSR-UHFFFAOYSA-N
• SMILES: CC1=C(C(=O)C2=C(C1=O)C=CC=C2O)CCNC(=O)C3=CC=CC=C3

STAT3-IN-11（Cat No.:I043495）is a selective inhibitor of Signal Transducer and Activator of Transcription 3 (STAT3), a transcription factor involved in regulating immune response, cell growth, survival, and inflammation. STAT3 is frequently activated in various cancers, contributing to tumor progression and resistance to therapy. By inhibiting STAT3, STAT3-IN-11 aims to disrupt oncogenic signaling, reduce tumor growth, and enhance the effectiveness of cancer treatments. This compound is being explored as a potential therapeutic for cancers driven by aberrant STAT3 activity, as well as for conditions related to chronic inflammation and autoimmune disorders.