STAT3-IN-13

• CAT Number: I043333
• CAS Number: 2248552-86-3
• Molecular Formula: C21H20N6O3S
• Molecular Weight: 436.49
• Purity: ≥95%
• Synonyms: 3-cyano-N-(4-methoxyphenyl)-2-[(1-methylpyrazole-4-carbonyl)amino]-5,7-dihydro-4H-thieno[2,3-c]pyridine-6-carboxamide
• InChI: InChI=1S/C21H20N6O3S/c1-26-11-13(10-23-26)19(28)25-20-17(9-22)16-7-8-27(12-18(16)31-20)21(29)24-14-3-5-15(30-2)6-4-14/h3-6,10-11H,7-8,12H2,1-2H3,(H,24,29)(H,25,28)
• InChIKey: WVYHDFDOBCBKGI-UHFFFAOYSA-N
• SMILES: CN1C=C(C=N1)C(=O)NC2=C(C3=C(S2)CN(CC3)C(=O)NC4=CC=C(C=C4)OC)C#N

STAT3-IN-13（Cat No.:I043333）is a selective inhibitor targeting Signal Transducer and Activator of Transcription 3 (STAT3), a key transcription factor involved in regulating cell survival, proliferation, and immune response. STAT3 is frequently dysregulated in various cancers, promoting tumor growth, metastasis, and resistance to therapy. By inhibiting STAT3, STAT3-IN-13 aims to block these pro-tumorigenic effects and enhance the immune system’s ability to target cancer cells. This compound is being studied for its potential in treating cancers driven by STAT3 activation, as well as inflammatory diseases and conditions associated with immune system dysfunction.