STAT3-IN-3

• CAT Number: I018981
• CAS Number: 2361304-26-7
• Molecular Formula: C₂₇H₂₆BrN₃O₆S
• Molecular Weight: 600.48
• Purity: ≥95%
• Target: Stem Cell/Wnt

STAT3-IN-3 (CAT: I018981) is a small molecule inhibitor that specifically targets signal transducer and activator of transcription 3 (STAT3), a transcription factor involved in various cellular processes including cell growth, survival, and immune response. STAT3 plays a critical role in cancer development and progression, and inhibiting its activity has been explored as a potential therapeutic strategy. STAT3-IN-3 has demonstrated inhibitory effects on STAT3 phosphorylation and transcriptional activity in cancer cells. It has shown promising anticancer activity, including induction of apoptosis and inhibition of tumor growth in preclinical studies. Further research is ongoing to evaluate its potential as an anti-cancer therapeutic agent.

Reference

[1]. Cai G, et al. Discovery of fluorescent coumarin-benzo[b]thiophene 1, 1-dioxide conjugates as mitochondria-targeting antitumor STAT3 inhibitors. Eur J Med Chem. 2019 Jul 15;174:236-251.