STAT6-IN-1

• CAT Number: I042892
• CAS Number: 1637532-68-3
• Molecular Formula: C33H37IN3O7P
• Molecular Weight: 745.54
• Purity: ≥95%
• Synonyms: [4-[(E)-4-[[(2S)-1-[(2S)-2-[(4-iodophenyl)-phenylcarbamoyl]pyrrolidin-1-yl]-3,3-dimethyl-1-oxobutan-2-yl]amino]-4-oxobut-2-en-2-yl]phenyl] dihydrogen phosphate
• InChI: InChI=1S/C33H37IN3O7P/c1-22(23-12-18-27(19-13-23)44-45(41,42)43)21-29(38)35-30(33(2,3)4)32(40)36-20-8-11-28(36)31(39)37(25-9-6-5-7-10-25)26-16-14-24(34)15-17-26/h5-7,9-10,12-19,21,28,30H,8,11,20H2,1-4H3,(H,35,38)(H2,41,42,43)/b22-21+/t28-,30+/m0/s1
• InChIKey: CGLGRSOJPUXNFA-YVXBOAIISA-N
• SMILES: C/C(=C\C(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)N(C2=CC=CC=C2)C3=CC=C(C=C3)I)C(C)(C)C)/C4=CC=C(C=C4)OP(=O)(O)O

STAT6-IN-1（Cat No.:I042892）is a selective inhibitor targeting the Signal Transducer and Activator of Transcription 6 (STAT6) pathway, which plays a critical role in regulating immune responses and inflammation. By inhibiting STAT6, this compound modulates the activation of genes involved in immune cell differentiation, particularly in Th2 cells, which are implicated in allergic reactions and autoimmune diseases. STAT6-IN-1 is being studied for its potential to treat conditions such as asthma, allergies, and certain cancers, by reducing the inflammatory response and promoting a balanced immune function.