For research use only. Not for therapeutic Use.
<p style=/line-height:25px/>Stauprimide is a small molecule that increases the efficiency of the directed differentiation of mouse and human ESCs; interacts with NME2 and inhibits its nuclear localization.<br>IC50 value:<br>Target: ESCs modulaotr<br>Stauprimide inhibits the nuclear localization of NME2, blocking and downregulating c-Myc expression. The expression of c-Myc is crucial for embryonic stem cell self-renewal, and intervention by Stauprimide allows for more efficient lineage-specific differentiation. NME2 is also indicated to be upregulated in certain cancers, indicating further application for the blocking action of Stauprimide.</p>
| Catalog Number | I001952 |
| CAS Number | 154589-96-5 |
| Synonyms | N-((5S,6S,7R,9S)-6-methoxy-5-methyl-14,16-dioxo-5,6,7,8,9,14,15,16-octahydro-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-7-yl)-N-methylbenzamide |
| Molecular Formula | C35H28N4O5 |
| Purity | ≥95% |
| Target | Transcription Factors |
| Solubility | DMSO 100 mg/ml; Water <1 mg/ml |
| Storage | Store at -20C |
| InChIKey | MQCCJEYZKWZQHU-MPRCCEKMSA-N |
| Reference | <p style=/line-height:25px/> </p> |
