For research use only. Not for therapeutic Use.
STD1T is a deubiquitinase USP2a inhibitor with an IC50 of 3.3 μM in Ub-AMC Assay[1].
STD1T inhibits USP2a enzymatic activity in a concentration dependent manner. STD1T shows selective inhibition of USP2a vs. USP7 at the concentrations of 10 µM and 2000 µM, respectively[1].
| Catalog Number | I036697 |
| CAS Number | 893075-58-6 |
| Synonyms | 2-[[2-[(5-thiophen-2-yl-1,2-oxazol-3-yl)methoxy]acetyl]amino]-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide |
| Molecular Formula | C19H19N3O4S2 |
| Purity | ≥95% |
| InChI | InChI=1S/C19H19N3O4S2/c20-18(24)17-12-4-1-2-5-14(12)28-19(17)21-16(23)10-25-9-11-8-13(26-22-11)15-6-3-7-27-15/h3,6-8H,1-2,4-5,9-10H2,(H2,20,24)(H,21,23) |
| InChIKey | NRPUXFKWYPJDFT-UHFFFAOYSA-N |
| SMILES | C1CCC2=C(C1)C(=C(S2)NC(=O)COCC3=NOC(=C3)C4=CC=CS4)C(=O)N |
| Reference | [1]. Marcin D Tomala, et al. Identification of small-molecule inhibitors of USP2a. Eur J Med Chem. 2018 Apr 25;150:261-267. |
