For research use only, not for therapeutic use.
STL127705(Cat No.:I019175)is a selective inhibitor of the protein kinase CK1δ, which plays a crucial role in regulating various cellular processes, including circadian rhythms and cell cycle progression. By targeting CK1δ, STL127705 aims to disrupt aberrant signaling pathways involved in cancer and other diseases. Preclinical studies suggest that this compound may enhance apoptosis in tumor cells and exhibit potential anti-cancer effects. Its specificity for CK1δ minimizes off-target effects, making STL127705 a promising candidate for further development in oncology and other therapeutic areas, with ongoing research to evaluate its efficacy and safety.
Catalog Number | I019175 |
CAS Number | 1326852-06-5 |
Molecular Formula | C₂₂H₂₀FN₅O₄ |
Purity | ≥95% |
Reference | [1]. Weterings E, et al. A novel small molecule inhibitor of the DNA repair protein Ku70/80. DNA Repair (Amst). 2016 Jul;43:98-106. |