For research use only. Not for therapeutic Use.
STM2120 is a METTL3-METTL14 inhibitor with an IC50 of 64.5 μM[1].
STM2120 (0.04-50 μM; 72 h) shows no effect on the proliferation of MOLM-13 cells[1].
| Catalog Number | I041134 |
| CAS Number | 2762286-04-2 |
| Synonyms | N-[(5-methylimidazo[1,2-a]pyridin-2-yl)methyl]-4-oxopyrido[1,2-a]pyrimidine-2-carboxamide |
| Molecular Formula | C18H15N5O2 |
| Purity | ≥95% |
| InChI | InChI=1S/C18H15N5O2/c1-12-5-4-7-15-20-13(11-23(12)15)10-19-18(25)14-9-17(24)22-8-3-2-6-16(22)21-14/h2-9,11H,10H2,1H3,(H,19,25) |
| InChIKey | BOTBQIXFHWFWHV-UHFFFAOYSA-N |
| SMILES | CC1=CC=CC2=NC(=CN12)CNC(=O)C3=CC(=O)N4C=CC=CC4=N3 |
| Reference | [1]. Yankova E, et al. Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia. Nature. 2021 May;593(7860):597-601. |
