For research use only. Not for therapeutic Use.
The STn (sialyl-Tn) epitope（Cat No.:R000511） is a tumor-associated carbohydrate antigen characterized by the aberrant expression of sialic acid on O-linked glycans of glycoproteins and glycolipids. It is commonly found on the surface of cancer cells, particularly in adenocarcinomas such as breast, ovarian, and colorectal cancers. The presence of STn is associated with tumor progression, metastasis, and poor prognosis. STn is recognized as a potential target for cancer immunotherapy and targeted drug delivery due to its tumor-specific expression, making it a focus of research for developing novel diagnostic and therapeutic strategies against cancer.
| CAS Number | 114661-01-7 |
| Synonyms | Serinyl 2-Acetamido-2-deoxy-6-O-(α-2-N-Acetylnuraminyl)-α-D-galactopyranosyl; ?6-O-α-Sialyl-2-acetamido-2-deoxy-α-D-galactopyranosyl-1-O-L-serine; O-[2-(acetylamino)-6-O-(N-acetyl-α-neuraminosyl)-2-deoxy-α-D-galactopyranosyl]-L-serine; |
| Molecular Formula | C₂₂H₃₇N₃O₁₆ |
| Purity | ≥95% |
| Storage | Store at RT |
| IUPAC Name | 5-acetamido-2-[[5-acetamido-6-(2-amino-2-carboxyethoxy)-3,4-dihydroxyoxan-2-yl]methoxy]-4-hydroxy-6-(1,2,3-trihydroxypropyl)oxane-2-carboxylic acid |
| InChI | InChI=1S/C22H37N3O16/c1-7(27)24-13-10(29)3-22(21(36)37,41-18(13)15(31)11(30)4-26)39-6-12-16(32)17(33)14(25-8(2)28)20(40-12)38-5-9(23)19(34)35/h9-18,20,26,29-33H,3-6,23H2,1-2H3,(H,24,27)(H,25,28)(H,34,35)(H,36,37) |
| InChIKey | RMINQIRDFIBNLE-UHFFFAOYSA-N |
| SMILES | CC(=O)NC1C(CC(OC1C(C(CO)O)O)(C(=O)O)OCC2C(C(C(C(O2)OCC(C(=O)O)N)NC(=O)C)O)O)O |
