For research use only. Not for therapeutic Use.
Streptazolin is an antibiotic. Streptazolin increases bacterial killing and elaboration of immunostimulatory cytokines by macrophages in vitro. Streptazolin stimulates the macrophage NF-κB pathway via PI3K signaling[1][2].
| Catalog Number | I044107 |
| CAS Number | 80152-07-4 |
| Synonyms | (4S,5S,6Z,11S)-6-ethylidene-5-hydroxy-3-oxa-1-azatricyclo[5.3.1.04,11]undec-7-en-2-one |
| Molecular Formula | C11H13NO3 |
| Purity | ≥95% |
| InChI | InChI=1S/C11H13NO3/c1-2-6-7-4-3-5-12-8(7)10(9(6)13)15-11(12)14/h2,4,8-10,13H,3,5H2,1H3/b6-2-/t8-,9-,10-/m0/s1 |
| InChIKey | OJIUACOQFBQCDF-IKXJTIOISA-N |
| SMILES | CC=C1C(C2C3C1=CCCN3C(=O)O2)O |
| Reference | [1]. Groenhagen U, et al. Streptopyridines, volatile pyridine alkaloids produced by Streptomyces sp. FORM5. Beilstein J Org Chem. 2014;10:1421-1432. Published 2014 Jun 24. [2]. Perry JA, et al. A macrophage-stimulating compound from a screen of microbial natural products. J Antibiot (Tokyo). 2015;68(1):40-46. |
