Streptomycin Sulfate

• CAT Number: A000241
• CAS Number: 3810-74-0
• Molecular Formula: (C₂₁H₃₉N₇O₁₂)₂ · 3H₂SO₄
• Molecular Weight: 1457.40
• Purity: ≥95%
• Target: Bacterial
• Storage: 3 years -20C powder
• IUPAC Name: 2-[(1R,2R,3S,4R,5R,6S)-3-(diaminomethylideneamino)-4-[(2R,3R,4R,5S)-3-[(2S,3S,4S,5R,6S)-4,5-dihydroxy-6-(hydroxymethyl)-3-(methylamino)oxan-2-yl]oxy-4-formyl-4-hydroxy-5-methyloxolan-2-yl]oxy-2,5,6-trihydroxycyclohexyl]guanidine;sulfuric acid
• InChI: InChI=1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;;;/m00.../s1
• InChIKey: QTENRWWVYAAPBI-YCRXJPFRSA-N
• SMILES: C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(C=O)O.C[C@H]1[C@@]([C@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H]([C@H]([C@@H]([C@H]2O)O)N=C(N)N)O)N=C(N)N)O[C@H]3[C@H]([C@@H]([C@H]([C@@H](O3)CO)O)O)NC)(C=O)O.OS(=O)(=O)O.OS(=O)(=O)O.OS(=O)(=O)O

Streptomycin Sulfate（Cat No.:A000241）is an aminoglycoside antibiotic primarily effective against Gram-negative bacteria and certain mycobacteria. It inhibits protein synthesis by binding to the 30S ribosomal subunit, causing misreading of mRNA and bacterial cell death. Widely used to treat tuberculosis and infections such as tularemia and plague, Streptomycin Sulfate is also employed in agricultural and laboratory settings for bacterial control and selection. Its potency and broad-spectrum activity make it essential in treating specific infections, though its use is limited by potential ototoxicity and nephrotoxicity with prolonged exposure.

Reference

Davis, Bernard D. /Mechanism of Bactericidal Action of Aminoglycosides./Microbiological Reviews 51.3 (1987): 341-50.McManus P.S., Stockwell V.O., Sundin G.W. and Jones A.L., 2002, Antibiotic use in plant agriculture. Annu. Rev. Phytopathol. 2002. 40:443–65