Strictosamide

• CAT Number: R024101
• CAS Number: 23141-25-5
• Molecular Formula: C26H30N2O8
• Molecular Weight: 498.53
• Purity: 98%
• Target: Parasite
• IUPAC Name: (1S,18S,19R,20S)-19-ethenyl-18-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,10.04,9.015,20]henicosa-2(10),4,6,8,15-pentaen-14-one
• InChI: InChI=1S/C26H30N2O8/c1-2-12-15-9-18-20-14(13-5-3-4-6-17(13)27-20)7-8-28(18)24(33)16(15)11-34-25(12)36-26-23(32)22(31)21(30)19(10-29)35-26/h2-6,11-12,15,18-19,21-23,25-27,29-32H,1,7-10H2/t12-,15+,18+,19-,21-,22+,23-,25+,26+/m1/s1
• InChIKey: LBRPLJCNRZUXLS-IUNANRIWSA-N
• SMILES: C=C[C@@H]1[C@@H]2C[C@H]3C4=C(CCN3C(=O)C2=CO[C@H]1O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO)O)O)O)C6=CC=CC=C6N4

Strictosamide（Cat No.:R024101）is a natural alkaloid glycoside isolated from plants in the Rubiaceae family, known for its diverse pharmacological properties. It exhibits significant antimicrobial, anti-inflammatory, and anticancer activities. Strictosamide’s antimicrobial effects target bacterial and fungal pathogens, while its anti-inflammatory properties modulate immune responses, making it a candidate for treating infectious and inflammatory diseases. Research also highlights its potential cytotoxic effects on cancer cells, indicating promise in oncology. As a bioactive compound, strictosamide continues to be explored in medicinal chemistry for novel therapeutic applications.

Reference

1.Li, Zan, et al. "Synthesis and biological evaluation of strictosamide derivatives with improved antiviral and antiproliferative activities." Chemical biology & drug design 86.4 (2015): 523-530.
2.Zhenzhen, S. U., et al. "Experimental Research on Effect of Strictosamide Injection on Cardiovascular System." World Science and Technology-Modernization of Traditional Chinese Medicine 7 (2014): 1558-1564.