Strontium Ranelate

• CAT Number: A000439
• CAS Number: 135459-87-9
• Molecular Formula: C12H6N2O8SSr2
• Molecular Weight: 513.49
• Purity: ≥95%
• Synonyms: 135459-87-9; Protelos; Protos; Distrontium renelate; Osseor
• Target: CaSR
• Solubility: Limited solubility
• Storage: -20°C
• IUPAC Name: distrontium;5-[bis(carboxylatomethyl)amino]-3-(carboxylatomethyl)-4-cyanothiophene-2-carboxylate
• InChI: InChI=1S/C12H10N2O8S.2Sr/c13-2-6-5(1-7(15)16)10(12(21)22)23-11(6)14(3-8(17)18)4-9(19)20;;/h1,3-4H2,(H,15,16)(H,17,18)(H,19,20)(H,21,22);;/q;2*+2/p-4
• InChIKey: XXUZFRDUEGQHOV-UHFFFAOYSA-J
• SMILES: C(C1=C(SC(=C1C#N)N(CC(=O)[O-])CC(=O)[O-])C(=O)[O-])C(=O)[O-].[Sr+2].[Sr+2]

Strontium Ranelate（Cat No.:A000439）is a medication used to treat osteoporosis, particularly in postmenopausal women and individuals at high risk of fractures. It has a dual mechanism of action: promoting bone formation by stimulating osteoblast activity and reducing bone resorption by inhibiting osteoclasts. This unique profile helps improve bone density and reduce the risk of vertebral and hip fractures. Strontium Ranelate is often prescribed when other treatments are unsuitable. However, it requires careful monitoring due to potential side effects, such as cardiovascular risks, making it a second-line option in osteoporosis management.

Reference

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3: Strontium ranelate discontinued. Drug Ther Bull. 2017 Aug;55(8):93-94. doi:
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4: Rodrigues TA, Sampaio AJB Junior, Nunes IDP, Cartágenes MSS, Garcia JBS.
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5: ▽ Strontium ranelate discontinued. Drug Ther Bull. 2017 Aug 2. doi:
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6: Pan WL, Chen PL, Lin CY, Pan YC, Ju YR, Chan CP, Hsu RW. Strontium ranelate
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9: Alves SM, Abreu SC, Lemos JC, Gomes FIF, Alves SM, do Val DR, Freitas RS,
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