Suberoylanilide-d5 Hydroxamic Acid β-D-Glucuronide

• CAT Number: R007038
• CAS Number: NA
• Molecular Formula: C₂₀H₂₃D₅N₂O₉
• Molecular Weight: 445.48
• Purity: ≥95%
• Synonyms: 1-O-[[1,8-Dioxo-8-(phenyl-d5-amino)octyl]amino]-β-D-glucopyranuronic Acid; Vorinostat-d5 glucuronide
• Storage: -20°C

Suberoylanilide-d5 Hydroxamic Acid β-D-Glucuronide（Cat No.:R007038） is a deuterated derivative of Suberoylanilide Hydroxamic Acid, enriched with five deuterium atoms. This compound is a glucuronide conjugate, facilitating its solubility and excretion, which is pivotal in pharmacokinetic studies, particularly for monitoring drug metabolism and clearance. The deuteration enhances the analytical detection, especially in mass spectrometry, making it invaluable for tracing the metabolic pathways of histone deacetylase inhibitors. This glucuronide form is crucial for understanding the drug’s distribution and elimination in the body, aiding in the optimization of therapeutic dosages and safety profiles.