Substance P (5-11) (TFA)

• CAT Number: I040810
• Molecular Formula: C41H60N10O9S.xC2HF3O2
• Molecular Weight: 869.04 (free base)
• Purity: ≥95%

Substance P (5-11) TFA(CAT: I040810) is the C-terminal heptapeptide fragment of Substance P, a well-known neuropeptide involved in pain transmission, inflammation, and neuroimmune responses. This fragment retains the core bioactive sequence responsible for binding to the neurokinin-1 (NK-1) tachykinin receptor, mediating various physiological and pathological processes. Substance P (5-11) TFA is commonly used in neuroscience and pharmacological studies to explore NK-1 receptor signaling, receptor binding specificity, and downstream cellular effects. Its truncated structure makes it a useful tool for dissecting the structure-activity relationship of Substance P and developing NK-1 receptor-targeted therapeutics for pain, mood disorders, and inflammatory diseases.