Suc-Gly-Pro-AMC

• CAT Number: I043836
• CAS Number: 80049-85-0
• Molecular Formula: C21H23N3O7
• Molecular Weight: 429.42
• Purity: ≥95%
• Synonyms: 4-[[2-[(2S)-2-[(4-methyl-2-oxochromen-7-yl)carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-4-oxobutanoic acid
• InChI: InChI=1S/C21H23N3O7/c1-12-9-20(29)31-16-10-13(4-5-14(12)16)23-21(30)15-3-2-8-24(15)18(26)11-22-17(25)6-7-19(27)28/h4-5,9-10,15H,2-3,6-8,11H2,1H3,(H,22,25)(H,23,30)(H,27,28)/t15-/m0/s1
• InChIKey: NKEPCOOQNLGSLJ-HNNXBMFYSA-N
• SMILES: CC1=CC(=O)OC2=C1C=CC(=C2)NC(=O)C3CCCN3C(=O)CNC(=O)CCC(=O)O

Suc-Gly-Pro-AMC is a fibroblast activation protein (FAP)-specific substrate. Suc-Gly-Pro-AMC can be used to study the activity of FAP[1].

Reference

[1]. Zhang B, et, al. A cell-based fluorescent assay for FAP inhibitor discovery. Bioorg Med Chem Lett. 2020 Jul 15;30(14):127253.
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