Suc-Leu-Leu-Val-Tyr-AMC

• CAT Number: R020629
• CAS Number: 94367-21-2
• Molecular Formula: C40H53N5O10
• Molecular Weight: 763.9
• Purity: ≥95%
• Synonyms: Suc-LLVY-AMC
• Storage: -20°C
• InChI: InChI=1S/C40H53N5O10/c1-21(2)16-29(42-33(47)14-15-34(48)49)38(52)43-30(17-22(3)4)39(53)45-36(23(5)6)40(54)44-31(19-25-8-11-27(46)12-9-25)37(51)41-26-10-13-28-24(7)18-35(50)55-32(28)20-26/h8-13,18,20-23,29-31,36,46H,14-17,19H2,1-7H3,(H,41,51)(H,42,47)
• InChIKey: UVFAEQZFLBGVRM-MSMWPWNWSA-N
• SMILES: CC(C1=CC=C(C=C1O2)NC([C@H](CC3=CC=C(C=C3)O)NC([C@@H](NC([C@@H](NC([C@@H](NC(CCC(O)=O)=O)CC(C)C)=O)CC(C)C)=O)C(C)C)=O)=O)=CC2=O

Suc-Leu-Leu-Val-Tyr-AMC is a fluorescent substrate for the 20S proteasome, other chymotrypsin-like proteases, and calpains (excitation max: 360 nm; emission max: 460 nm).

Reference

1.Geier, E.,Pfeifer, G.,Wilm, M., et al. A giant protease with potential to substitute for some functions of the proteasome. Science 283(5404), 978-981 (1999).