Succinylacetone pyrrole

• CAT Number: I036760
• CAS Number: 80037-86-1
• Molecular Formula: C12H15NO5
• Molecular Weight: 253.25
• Purity: 98%
• Synonyms: Succinylacetone pyrrole; SA-Pyrrole
• Solubility: Soluble in DMSO
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 4-(4-(2-carboxyethyl)-2-methyl-1H-pyrrol-3-yl)-4-oxobutanoic acid
• InChI: InChI=1S/C12H15NO5/c1-7-12(9(14)3-5-11(17)18)8(6-13-7)2-4-10(15)16/h6,13H,2-5H2,1H3,(H,15,16)(H,17,18)
• InChIKey: NRCLTECUGCYICQ-UHFFFAOYSA-N
• SMILES: O=C(O)CCC(C1=C(C)NC=C1CCC(O)=O)=O

Succinylacetone Pyrrole(CAT: I036760) is a derivative of succinylacetone, studied for its role in biochemical and metabolic research. Known for its ability to inhibit heme biosynthesis by targeting 5-aminolevulinate dehydratase (ALAD), this compound is instrumental in exploring disorders such as porphyria and tyrosinemia type I. Its pyrrole structure enhances its utility in examining metabolic intermediates and enzyme-substrate interactions. Succinylacetone Pyrrole is also employed in research on oxidative stress and cellular metabolism, offering a valuable tool for investigating therapeutic approaches to metabolic and hematological diseases.