For research use only. Not for therapeutic Use.
SUCNR1-IN-1 (CAT: I040898) is a potent inhibitor of the SUCNR1 (succinate receptor 1) with an IC50 value of 88 nM for human SUCNR1. SUCNR1 plays a critical role in inflammatory pathways and is implicated in various diseases, including rheumatoid arthritis, liver fibrosis, and obesity. By inhibiting SUCNR1, this compound has the potential to modulate inflammatory responses and metabolic processes, offering a novel therapeutic approach for these conditions. SUCNR1-IN-1 is relevant for research in Inflammation & Immunology Research, Metabolic Disease Research, and Fibrosis, providing a promising tool for investigating the therapeutic targeting of SUCNR1 in chronic diseases.
| CAS Number | 2711753-52-3 |
| Synonyms | 2-[2-[[3-[4-chloro-2-fluoro-5-[(3R)-piperidin-3-yl]oxyphenyl]-2-fluorobenzoyl]amino]-5-fluorophenyl]acetic acid |
| Molecular Formula | C26H22ClF3N2O4 |
| Purity | ≥95% |
| IUPAC Name | 2-[2-[[3-[4-chloro-2-fluoro-5-[(3R)-piperidin-3-yl]oxyphenyl]-2-fluorobenzoyl]amino]-5-fluorophenyl]acetic acid |
| InChI | InChI=1S/C26H22ClF3N2O4/c27-20-12-21(29)19(11-23(20)36-16-3-2-8-31-13-16)17-4-1-5-18(25(17)30)26(35)32-22-7-6-15(28)9-14(22)10-24(33)34/h1,4-7,9,11-12,16,31H,2-3,8,10,13H2,(H,32,35)(H,33,34)/t16-/m1/s1 |
| InChIKey | MOOARNYDOKGVQG-MRXNPFEDSA-N |
| SMILES | C1CC(CNC1)OC2=C(C=C(C(=C2)C3=C(C(=CC=C3)C(=O)NC4=C(C=C(C=C4)F)CC(=O)O)F)F)Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
